About: Transition metal-based anticancer compounds. From mechanistic studies to innovatory cancer chemotherapy     Goto   Sponge   NotDistinct   Permalink

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  • The main objective is to increase knowledge and understanding of the mechanisms of action of antitumour metallodrugs, and to use this enhanced knowledge in combination with modern genomic research to develop new classes of metallodrugs with truly novel mechanisms of action and novel spectra of biomedical activity. (en)
  • Cílem tohoto výzkumu je zjistit údaje o molekulárních mechanismech protinádorového působení metalofarmak odvozených od přechodných kovů. Nové znalosti získané při řešení tohoto projektu využít pro návrhy nových typů cytostatik (cs)
Title
  • Transition metal-based anticancer compounds. From mechanistic studies to innovatory cancer chemotherapy (en)
  • Protinádorově účinné sloučeniny přechodných kovů. Od mechanistických studií k inovacím v chemoterapii rakoviny (cs)
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  • Cancer; chemotherapy; antitumor drugs; DNA; platinum; ruthenium; antitumor activity (en)
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