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  • PK parametr acikloviru 250 mg (N=15) 500 mg (N=15) 1000 mg (N=15) 2000 mg (N=8) Cmax mikrogramy/ml 2,20 ± 0,38 3,37 ± 0,95 5,20 ± 1,92 8,30 ± 1,43 tmax hodiny (h) 0,75 (0,75-1,5) 1,0 (0.75-2,5) 2,0 (0,75-3,0) 2,0 (1,5-3,0) AUC h.mikrogramy/ml 5,50 ± 0,82 11,1 ± 1,75 18,9 ± 4,51 29,5 ± 6,36 Cmax = vrcholová (maximální) plazmatická koncentrace; tmax = průměrný čas dosažení maximální sérové koncentrace; AUC = plocha pod křivkou plazmatické koncentrace. (cs)
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