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  • U pacientů se středně závažným poškozením se AUC zvyšuje 2,4x (CrCL 33-74 ml/min), 5x u závažného poškození (CrCL 4-23 ml/min) a 10x u hemodialyzovaných pacientů (CrCL < 2 ml/min) ve srovnání se zdravými jedinci (CrCL > 80 ml/min). (cs)
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