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  • které jsou minimálně jeden rok po menarché) ve věku 10 – 17 let (průměrný věk 14,1 let) s heterozygotní familiární hypercholesterolémií (heFH) randomizováno do skupiny pro simvastatin nebo placebo po dobu 24 týdnů (výchozí studie).<0} {0>Inclusion in the study required a baseline LDL-C level between 160 and 400 mg/dL and at least one parent with an LDL-C level > 189 mg/dL.<}0{>Zařazení do studie vyžadovalo výchozí hladinu LDL-C mezi 160 a 400 mg/dl a minimálně jednoho rodiče s hladinou LDL-C > 189 mg/dl.<0} {0>The dosage of simvastatin (once daily in the evening) was 10 mg for the first 8 weeks, 20 mg for the second 8 weeks, (cs)
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