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  • Souhrn hlavních farmakokinetických parametrů u pacientů, kterým byly podávány intravenózní infuze raltitrexedu 3,0 mg/ m2 Cmax (ng/ml) AUC0-inf (ng.h/ml) CL (ml/min) CLr (ml/min) Vss (1) t1/2beta (h) t1/2gamma (h) 656 1856 51.6 25.1 548 1.79 198 Maximální koncentrace raltitrexedu v rozsahu klinicky testovaných dávek narůstají lineárně s dávkou. (cs)
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