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  • Farmakodynamické účinky V dvojitě zaslepené placebem kontrolované EKG studii u zdravých dobrovolníků byla změna proti počáteční hodnotě QTc (měřená s korekcí dle Fridericia) 4,3 msec (90% Cl: 2,2; 6,4) při dávce 10 mg/den a 10,7 msec (90% Cl: 8,6;, 12,8) při supraterapeutické dávce 30 mg/den (viz body 4.3, 4.4, 4.5, 4.8 a 4.9). (cs)
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