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  • Tabulka 16 Vztah expozice-odpověď pro everolimus u pacientů po transplantaci Transplantace ledvin Minimální hladina (ng/ml) ≤ 3,4 3,5 - 4,5 4,6 - 5,7 5,8 - 7,7 7,8 - 15,0 Bez rejekce 68% 81% 86% 81% 91% Trombocytopenie (<100x109/l) 10% 9% 7% 14% 17% Transplantace srdce Minimální hladina (ng/ml) ≤ 3,5 3,6 - 5,3 5,4 - 7,3 7,4 - 10,2 10,3 - 21,8 Bez rejekce 65% 69% 80% 85% 85% Trombocytopenie (<75x109/l) 5% 5% 6% 8% 9% Transplantace jater Minimální hladina (ng/ml) ≤ 3 3 - 8 ≥ 8 Bez léčené BPAR 88% 98% 92% Trombocytopenie (≤75x109/l) 35% 13% 18% (cs)
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