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  • Pokud se u pacientù s výskytem tìžké neutropenie (poèet neutrofilù < 0,5 x 109/l) trvající 7 nebo více dní nebo u pacientù s tìžkou neutropenií spojenou s horeèkou nebo infekcí, pøípadnì u pacientù, u nichž byla terapie vzhledem k neutropenii zpoždìna, snižuje dávka, mìla by být snížena pro následné cykly o 20% na 0,6 mg/m2/den (nebo následnì až na 0,45 mg/m2/den, pokud je to nezbytné). (cs)
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