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  • V případě průjmu 4. stupně, neutropenie 3. - 4. stupně (počet neutrofilů <1,0x109/l), trombocytopenie 3. - 4. stupně (počet trombocytů < 50x109/l) by měla být dávka oxaliplatiny snížena z 85 na 65 mg/m2 (léčba metastáz) nebo na 75 mg/m2 (adjuvantní léčba) za současného snížení dávky 5-fluorouracilu podle potřeby. (cs)
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