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  • Ve studii HPS (viz 5.1, Farmakodynamické vlastnosti) s 20.536 pacienty, kterým se podával buď simvastatin v denní dávce 40 mg (n = 10.269) anebo přípravek placeba (n = 10.267) byly po celou střední dobu sledování, tj. po 5 let, bezpečnostní profily u pacientů se 40 mg simvastatinu srovnatelné s profily u pacientů, kteří dostávali placebo. (cs)
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