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  • Režimy chemoterapie u osteosarkomu Lék Dávka Týden léčby po chirurg. zákroku Metotrexát 12 g/m2 jako 4hodinová infuze 4, 5, 6, 7, 11, 12, 15, 16, 29, 30, 44, 45 Leukovorin 15 mg p.o. každých 6 hodin, celkem 10 dávek zahájených 24 hod. po začátku infuze s metotrexátem Doxorubicin* jako monoterapie 30 mg/m2/den i.v. po 3 dny 8, 17 Doxorubicin* Cisplatina* 50 mg/m2 i.v. 100 mg/m2 i.v. 20, 23, 33, 36 20, 23, 33, 36 Bleomycin* Cyklofosfamid* Daktinomycin* 15 jedn./m2 i.v. po 2 dny 600 mg/m2 i.v. po 2 dny 0,6 mg/m2 i.v. po 2 dny 2, 13, 26, 39, 42 2, 13, 26, 39, 42 2, 13, 26, 39, 42 * detailní informace viz. monografie příslušných přípravků. (cs)
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