About: 5-FITC-labeled GI-heptapeptide     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • 5-FITC-labeled GI-heptapeptide
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • 5-FITC-labeled GI-heptapeptide
NCI_META_CUI
  • CL430315
PDQ_Open_Trial_Search_ID
  • 706325
PDQ_Closed_Trial_Search_ID
  • 706325
FULL_SYN
  • 5-FITC-labeled 7-AA PeptideSYNCI
  • 5-FITC-labeled GI-heptapeptidePTNCI
  • Ala1-Ser2-Tyr3-Asn4-Tyr5-Asp6-Ala7-Gly8- Gly9-Gly10-Ser11-Lys12 (5-FITC) -NH213SYNCI
DEFINITION
  • A radioconjugate consisting of the 7 amino acid peptide sequence ASYNYDA (GI heptapeptide) and labeled with the fluorescent dye fluorescein isothiocyanate (5-FITC), with potential imaging activity. Upon topical application to the esophageal mucosa using a spray, the heptapeptide moiety of 5-FITC-labeled GI-heptapeptide binds to abnormal cells in the esophagus; the FITC moiety allows for imaging with white light and the area of interest for biopsies can then be visualized.NCI
code
  • C97659
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