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AttributesValues
rdf:type
rdfs:label
  • Ipomeanol
rdfs:subClassOf
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Ipomeanol
NSC_Code
  • 349438
UMLS_CUI
  • C0048420
CAS_Registry
  • 32954-58-8
PDQ_Open_Trial_Search_ID
  • 38852
PDQ_Closed_Trial_Search_ID
  • 38852
Legacy_Concept_Name
  • Ipomeanol
FULL_SYN
  • 4-ipomeanolSYNCI
  • 1-(3-furanyl)-4-hydroxy-1-pentanoneSNNCI
  • 1-Pentanone, 1-(3-furanyl)-4-hydroxy-SYDTPNSC0349438
  • 1-(3-Furanyl)-4-hydroxy-1-pentanonePTDCP00822
  • IpomeanolPTNCI
  • 4-IpomeanolSYDTPNSC0349438
DEFINITION
  • A natural toxic furan isolated from a fungus-infected sweet potato (Ipomoea batatas) with potential antineoplastic activity. Ipomeanol is activated by mixed function oxidases in vivo to its epoxide form, an alkylating agent that covalently binds cell macromolecules. This agent causes cell death by a p53-independent mechanism. (NCI04)NCI
code
  • C976
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