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AttributesValues
rdf:type
rdfs:label
  • Paclitaxel Ceribate
rdfs:subClassOf
Has_Target
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Paclitaxel Ceribate
NCI_META_CUI
  • CL429502
CAS_Registry
  • 186040-50-6
FDA_UNII_Code
  • B3C86E80A0
Contributing_Source
  • FDA
Chemical_Formula
  • C51H57NO18
FULL_SYN
  • 7beta-((2RS)-2,3-dihydroxypropoxycarbonyloxy)-1-hydroxy-9-oxo-5beta,20-epoxytax-11-ene-2alpha,4,10beta,13alpha-tetrayl 4,10-diacetate 2-benzoate 13-((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoate)SNNCI
  • Paclitaxel CeribatePTNCI
  • PACLITAXEL CERIBATEPTFDAB3C86E80A0
DEFINITION
  • The ceribate ester form of paclitaxel, a compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to and stabilizes tubulin thereby inhibiting the disassembly of microtubules, resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein B-cell Leukemia 2 (BCL2).NCI
code
  • C96934
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