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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • 18-F-fluoroacetate
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • 18-F-fluoroacetate
NCI_META_CUI
  • CL429016
PDQ_Open_Trial_Search_ID
  • 698007
PDQ_Closed_Trial_Search_ID
  • 698007
FULL_SYN
  • Fluorine F 18 FluoroacetateSYNCI
  • 18-F-fluoroacetatePTNCI
  • (18)F-FACABNCI
DEFINITION
  • A radioconjugate and an acetate analog labeled with fluorine F 18 ((18)F-FAC), a positron-emitting isotope, with potential prostate tumor tracer property using positron emission tomography (PET). Although the mechanism of action is unclear, fluorine F 18 acetate preferentially accumulates in tumor tissue, serving as a tracer for imaging tumors with PET. Fluorine 18 has a longer radioactive half-life (110 min) vs. the half-life of carbon-11 acetate (20.4 min). Furthermore, (18)F-FAC showed a rapid clearance from liver and extensive excretion to bile and urine in comparison with carbon-11 acetate, therefore this tracer may be a useful alternative to C-11 acetate for the detection of prostate tumors by PET.NCI
code
  • C96236
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