About: Azidocillin Potassium     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Azidocillin Potassium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Azidocillin Potassium
UMLS_CUI
  • C2986960
CAS_Registry
  • 22647-32-1
FDA_UNII_Code
  • 7932098147
Contributing_Source
  • FDA
Chemical_Formula
  • C16H16N5O4S.K
FULL_SYN
  • AZIDOCILLIN POTASSIUMPTFDA7932098147
  • 4-Thia-1-Azabicyclo(3.2.0)Heptane-2-Carboxylic Acid,6-((Azidophenylacetyl)Amino)-3,3-Dimethyl-7-Oxo-, Monopotassium Salt, (2s-(2.Alpha.,5.Alpha.,6.Beta.(S*)))-SNNCI
  • D-(-)-.Alpha.-Azidobenzylpenicillin Potassium SaltSYNCI
  • Azidocillin PotassiumPTNCI
DEFINITION
  • The potassium salt of a narrow-spectrum, semisynthetic penicillin derivative with antibacterial activity. Azidocillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.NCI
code
  • C95169
is Has_Salt_Form of
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