About: Pentosan Polysulfate Sodium     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Pentosan Polysulfate Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Carbohydrate
  • Pharmacologic Substance
Preferred_Name
  • Pentosan Polysulfate Sodium
UMLS_CUI
  • C0524684
CAS_Registry
  • 140207-93-8
FDA_UNII_Code
  • 914032762Y
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 40350
PDQ_Closed_Trial_Search_ID
  • 40350
Chemical_Formula
  • (C5H6Na2O10S2)n
Legacy_Concept_Name
  • Pentosan_Polysulfate_Sodium
FULL_SYN
  • Tavan SP-54FBNCI
  • Sodium Xylan PolysulfateSYNCI
  • Sodium Pentosan PolysulfateSYNCI
  • Pentosan Polysulfate SodiumPTNCI
  • FibraseBRNCI
  • ElmironBRNCI
  • FibrocidFBNCI
  • HemoclarFBNCI
  • FibrezymFBNCI
  • PentosanSYNCI
  • PENTOSAN POLYSULFATE SODIUMPTFDA914032762Y
  • ThrombocidFBNCI
  • CartrophenBRNCI
  • HOE-BAY 946FBNCI
DEFINITION
  • The sodium salt of a semisynthetic heparin-like glucosaminoglycan. Although its mechanism of action is unknown, pentosan polysulfate may act as a buffer to control cell permeability by preventing irritating solutes from reaching cells coated with it. Administered orally, excreted pentosan polysulfate adheres to the urinary bladder wall, preventing irritants from entering bladder cells and the development or progression of interstitial cystitis (IC), a complication of some chemotherapies. This agent also exhibits anticoagulant and fibrinolytic properties.NCI
code
  • C946
is Has_Salt_Form of
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