About: Iron Isomaltoside 1000     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Iron Isomaltoside 1000
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Iron Isomaltoside 1000
NCI_META_CUI
  • CL421631
PDQ_Open_Trial_Search_ID
  • 680696
PDQ_Closed_Trial_Search_ID
  • 680696
FULL_SYN
  • Iron Isomaltoside 1000PTNCI
  • MonoferBRNCI
DEFINITION
  • An intravenous colloidal solution containing trivalent iron (Fe3+) chelated to isomaltosides, used as iron replacement. The iron in iron isomaltoside 1000 is strongly bound to the carbohydrate particles; each particle contains a trivalent iron core and a carbohydrate shell of isomaltosides which protects and stabilizes the iron core. This results in low levels of free iron and decreases inorganic, unbound iron-related toxicities thereby allowing for administration of higher doses of iron as compared to other iron-containing formulations. Upon parenteral administration and degradation of the carbohydrate shell, the iron in iron isomaltoside 1000 is released and replenishes iron stores.NCI
code
  • C92584
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