About: ECM-Receptor Interaction Signaling Pathway

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About: ECM-Receptor Interaction Signaling Pathway Goto Sponge NotDistinct Permalink

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Attributes	Values
rdf:type	Class
rdfs:label	ECM-Receptor Interaction Signaling Pathway
rdfs:subClassOf	Signaling Pathway
Semantic_Type	Functional Concept
Preferred_Name	ECM-Receptor Interaction Signaling Pathway
UMLS_CUI	C2984324
KEGG_ID	hsa04512
ALT_DEFINITION	The extracellular matrix (ECM) consists of a complex mixture of structural and functional macromolecules and serves an important role in tissue and organ morphogenesis and in the maintenance of cell and tissue structure and function. Specific interactions between cells and the ECM are mediated by transmembrane molecules, mainly integrins and perhaps also proteoglycans, CD36, or other cell-surface-associated components. These interactions lead to a direct or indirect control of cellular activities such as adhesion, migration, differentiation, proliferation, and apoptosis. In addition, integrins function as mechanoreceptors and provide a force-transmitting physical link between the ECM and the cytoskeleton. Integrins are a family of glycosylated, heterodimeric transmembrane adhesion receptors that consist of noncovalently bound alpha- and beta-subunits.KEGG
FULL_SYN	ECM-receptor interactionPTKEGG ECM-Receptor Interaction Signaling PathwayPTNCI
code	C91515
is someValuesFrom of	nodeID://b649679 nodeID://b679074 nodeID://b681995 nodeID://b682050 nodeID://b682096 nodeID://b682907 nodeID://b682996 nodeID://b683039 nodeID://b698358 nodeID://b706841 nodeID://b708488 nodeID://b709741 nodeID://b709748 nodeID://b710825 nodeID://b716479 nodeID://b716492

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