About: Cytosolic DNA-Sensing Pathway

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Cytosolic DNA-Sensing Pathway Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Cytosolic DNA-Sensing Pathway
rdfs:subClassOf	Signaling Pathway
Semantic_Type	Functional Concept
Preferred_Name	Cytosolic DNA-Sensing Pathway
UMLS_CUI	C2984314
KEGG_ID	hsa04623
ALT_DEFINITION	Specific families of pattern recognition receptors are responsible for detecting foreign DNA from invading microbes or host cells and generating innate immune responses. DAI is the first identified sensor of cytosolic DNA which activates the IRF and NF-kappa B transcription factors, leading to production of type I interferon and other cytokines. The second type of cytoplasmic DNA sensor is AIM2. Upon sensing DNA, AIM2 triggers the assembly of the inflammasome, culminating in interleukin maturation. In addition to these receptors, there is a mechanism to sense foreign DNA, with the host RNA polymerase III converting the DNA into RNA for recognition by the RNA sensor RIG-I. These pathways provide various means to alert the cell.KEGG
FULL_SYN	Cytosolic DNA-Sensing PathwayPTNCI Cytosolic DNA-sensing pathwayPTKEGG
code	C91504
is someValuesFrom of	nodeID://b646441 nodeID://b652430 nodeID://b657825 nodeID://b665088 nodeID://b681302 nodeID://b681604 nodeID://b682670 nodeID://b683889 nodeID://b695036 nodeID://b695253 nodeID://b701455 nodeID://b704296 nodeID://b706794 nodeID://b707012 nodeID://b707046 nodeID://b708094 nodeID://b708132 nodeID://b717852 nodeID://b720904

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 49 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software