About: Piritrexim Isethionate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Piritrexim Isethionate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Piritrexim Isethionate
NSC_Code
  • 351521
UMLS_CUI
  • C1522061
CAS_Registry
  • 79483-69-5
FDA_UNII_Code
  • V77I71FH72
Contributing_Source
  • FDA
Chemical_Formula
  • C17H19N5O2.C2H6O4S
FULL_SYN
  • Piritrexim IsethionatePTNCI
  • PIRITREXIM ISETHIONATEPTFDAV77I71FH72
  • 2,4-Diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido(2,3-d)pyrimidine mono(2-hydroxyethanesulfonate)SNNCI
  • Piritrexim isethionateSYDTPNSC0351521
  • BW-301U IsethionateSYNCI
DEFINITION
  • The isethionate salt of piritrexim, a synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties. Piritrexim inhibits the enzyme dihydrofolate reductase enzyme, thereby disrupting folate metabolism and DNA synthesis and cell division.NCI
code
  • C91407
is Has_Salt_Form of
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