About: Trimethoprim-Sulfamethoxazole     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Trimethoprim-Sulfamethoxazole
rdfs:subClassOf
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Trimethoprim-Sulfamethoxazole
NSC_Code
  • 618652
UMLS_CUI
  • C0041044
CAS_Registry
  • 8064-90-2
Accepted_Therapeutic_Use_For
  • Pneumocystis carinii pneumonia; Various bacterial infections
In_Clinical_Trial_For
  • HIV infections; Infection prevention in multiple myeloma
ALT_DEFINITION
  • An antibiotic drug used to treat infection and prevent pneumocystis carinii pneumonia.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39724
PDQ_Closed_Trial_Search_ID
  • 39724
Legacy_Concept_Name
  • Trimethoprim-Sulfamethoxazole
CHEBI_ID
  • CHEBI:3770
FULL_SYN
  • CotrimoxazoleSYNCI
  • Co-TrimoxazoleSYNCI
  • SulfamethoprimBRNCI
  • Co-TrimoxazoleSYDTPNSC0618652
  • BactrimSYDTPNSC0147832
  • CotrimBRNCI
  • SeptraBRNCI
  • co-trimoxazolePTNCI-GLOSSCDR0000045244
  • TMP-SMXABNCI
  • SMZ-TMPABNCI
  • BactrimBRNCI
  • CentranSYNCI
  • CentrinSYNCI
  • UroplusBRNCI
  • Trimethoprim-SulfamethoxazolePTNCI
  • EslectinSYNCI
  • TrimedinSYNCI
  • BactrimelSYNCI
  • SulfatrimBRNCI
  • InsozalinSYNCI
  • SulmeprimBRNCI
  • TrimezoleSYNCI
  • Bactrim DSBRNCI
  • trimethoprim-sulfamethoxazolePTNCI-GLOSSCDR0000046089
DEFINITION
  • A synthetic combination of two antibacterial agents, trimethoprim and sulfamethoxazole. This synergistic combination, also known as Co-Trimoxazole, inhibits two sequential steps in the bacterial metabolism of folic acid. Trimethoprim is a pyrimidine inhibitor of dihydrofolate reductase; sulfamethoxazole is a sulfamide inhibitor of bacterial dihydrofolate synthase.NCI
code
  • C909
is someValuesFrom of
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