About: Trifluoperazine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Trifluoperazine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Trifluoperazine Hydrochloride
NSC_Code
  • 17474
UMLS_CUI
  • C0304381
CAS_Registry
  • 440-17-5
FDA_UNII_Code
  • 6P1Y2SNF5V
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 40446
PDQ_Closed_Trial_Search_ID
  • 40446
Chemical_Formula
  • C21H24F3N3S.2HCl
Legacy_Concept_Name
  • Trifluoperazine
CHEBI_ID
  • CHEBI:9710
FULL_SYN
  • JatroneuralFBNCI
  • TRIFLUOPERAZINE HYDROCHLORIDEPTFDA6P1Y2SNF5V
  • 10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-10H-phenothiazine DihydrochlorideSNNCI
  • Trifluoperazine HydrochloridePTNCI
  • SKF 5019CNNCI
  • EskazineFBNCI
  • StelazineBRNCI
  • Trifluoperazine DihydrochlorideSYNCI
  • TerfluzineFBNCI
DEFINITION
  • The hydrochloride salt of trifluoperazine, a phenothiazine derivative and a dopamine, alpha-adrenergic, and anticholinergic antagonist with antipsychotic, anxiolytic, and antiemetic activities. Trifluoperazine blocks central dopamine receptors, which may prevent or mitigate delusions and hallucinations caused by an excess of dopamine; dopamine blockade in the chemoreceptor trigger zone (CTZ) may result in an antiemetic effect. This agent binds to central adrenergic receptors, which may result in anxiolytic effects. Trifluoperazine also functions as a calmodulin inhibitor, elevating cytosolic calcium.NCI
code
  • C904
is someValuesFrom of
is Has_Salt_Form of
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