About: Multikinase Inhibitor SAR103168     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Multikinase Inhibitor SAR103168
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Multikinase Inhibitor SAR103168
NCI_META_CUI
  • CL412467
PDQ_Open_Trial_Search_ID
  • 656309
PDQ_Closed_Trial_Search_ID
  • 656309
FULL_SYN
  • SAR103168CNNCI
  • Multikinase Inhibitor SAR103168PTNCI
DEFINITION
  • A multikinase inhibitor with potential antineoplastic activity. Upon intravenous infusion, multikinase inhibitor SAR103168 may, through the inhibition of multiple kinases, inhibit the phosphorylation and activation of signal transducer and activator of transcription 5 (STAT5). STAT5, a protein often upregulated in cancer cells, plays a key role in signal transduction pathways and the suppression of apoptosis.NCI
code
  • C88278
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