About: Mezlocillin Sodium Monohydrate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Mezlocillin Sodium Monohydrate
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Mezlocillin Sodium Monohydrate
UMLS_CUI
  • C2828283
CAS_Registry
  • 80495-46-1
FDA_UNII_Code
  • 3CWW8B5904
Contributing_Source
  • FDA
Chemical_Formula
  • C21H24N5O8S2.Na.H2O
CHEBI_ID
  • CHEBI:52068
FULL_SYN
  • MEZLOCILLIN SODIUM MONOHYDRATEPTFDA3CWW8B5904
  • Mezlocillin Sodium MonohydratePTNCI
DEFINITION
  • The monohydrate and sodium salt form of mezlocillin, a broad-spectrum, semisynthetic ampicillin-derived acylureidopenicillin with antibacterial activity. Mezlocillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.NCI
code
  • C87369
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