About: Peretinoin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Peretinoin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Peretinoin
UMLS_CUI
  • C2828216
CAS_Registry
  • 81485-25-8
FDA_UNII_Code
  • 11ALM7A4RV
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 737371
PDQ_Closed_Trial_Search_ID
  • 737371
Chemical_Formula
  • C20H30O2
FULL_SYN
  • NIK-333CNNCI
  • PERETINOINPTFDA11ALM7A4RV
  • (2E,4E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,4,6,10,14-Pentaenoic AcidSNNCI
  • PeretinoinPTNCI
DEFINITION
  • An orally available, acyclic retinoid with potential antineoplastic and chemopreventive activities. Peretinoin binds to and activates nuclear retinoic acid receptors (RAR), which in turn recruit coactivator proteins and promote, with other transcriptional complexes, the transcription of target genes. As a result, this agent may modulate the expression of genes involved in the regulation of cell proliferation, cell differentiation, and apoptosis of both normal and tumor cells.NCI
code
  • C87202
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software