About: Resveratrol Formulation SRT501     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Resveratrol Formulation SRT501
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Resveratrol Formulation SRT501
UMLS_CUI
  • C2002402
PDQ_Open_Trial_Search_ID
  • 648245
PDQ_Closed_Trial_Search_ID
  • 648245
FULL_SYN
  • SRT501CNNCI
  • Resveratrol Formulation SRT501PTNCI
DEFINITION
  • A proprietary formulation of resveratrol, a polyphenolic phytoalexin derived from grapes and other food products with potential antioxidant, anti-obesity, antidiabetic and chemopreventive activities. Resveratrol may activate sirtuin subtype 1 (SIRT-1). SIRT1 activation has been reported to inhibit tumorigenesis and tumor cell proliferation. SIRT-1 is a member of the silent information regulator 2 (SIR2) (or sirtuin) family of enzymes that plays an important role in mitochondrial activity and acts as a protein deacetylase. SIRT1 appears to be involved in the regulation of numerous transcription factors such as NF-kB and p53.NCI
code
  • C85484
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