About: Iodine I 123 Iodobenzamide     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Iodine I 123 Iodobenzamide
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Iodine I 123 Iodobenzamide
UMLS_CUI
  • C0090273
PDQ_Open_Trial_Search_ID
  • 643573
PDQ_Closed_Trial_Search_ID
  • 643573
FULL_SYN
  • Iodine I 123 IodobenzamidePTNCI
  • 123I-IBZMABNCI
DEFINITION
  • A radiopharmaceutical containing the dopamine D2/D3 receptor agonist iodobenzamide (IBZM) labeled with the radionuclide iodine I 123 with dopamine receptor-binding and radioisotopic activities. Upon administration, iodine I 123 iodobenzamide binds to dopamine D2/D3 receptors; subsequently, tissues expressing these receptors can be visualized using single photon emission computed tomography (SPECT). Dopamine receptors are a class of metabotropic G protein-coupled receptors found in the central nervous system (CNS) and neuroendocrine tumors such as pheochromocytoma and paraganglioma.NCI
code
  • C85461
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