About: Recombinant Somatostatin

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Attributes	Values
rdf:type	Class
rdfs:label	Recombinant Somatostatin
rdfs:subClassOf	Therapeutic Hormone
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Is_Related_To_Endogenous_Product	Somatostatin
Semantic_Type	Amino Acid, Peptide, or Protein Pharmacologic Substance
Preferred_Name	Recombinant Somatostatin
UMLS_CUI	C1881011
CAS_Registry	38916-34-6
FDA_UNII_Code	6E20216Q0L
Contributing_Source	FDA
Chemical_Formula	C76H104N18O19S2
Legacy_Concept_Name	Growth_Hormone_Release_Inhibiting_Factor
CHEBI_ID	CHEBI:64628
FULL_SYN	SOMATOSTATINPTFDA6E20216Q0L Growth Hormone Inhibiting HormoneSYNCI Recombinant SomatostatinPTNCI SRIFABNCI SomatostatinPTDCP30368 GH-RIHABNCI Somatotropin Release Inhibiting FactorSYNCI AY 24910CNNCI PanhibinAQSNCI
DEFINITION	A recombinant peptide chemically identical or similar to endogenous somatostatin. Somatostatin is a cyclic tetradecapeptide regulating many endocrine and nervous system functions. Somatostatin inhibits release of adenohypophyseal growth hormone, thyrotropin and corticotropin, pancreatic insulin and glucagon, gastric mucosal gastrin, intestinal mucosal secretin, and renal renin by binding to specific somatostatin receptors (SSTR), which are cell surface G protein-coupled receptors expressed in a tissue-specific manner.NCI
code	C836

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