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AttributesValues
rdf:type
rdfs:label
  • Maribavir
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Maribavir
UMLS_CUI
  • C1508759
CAS_Registry
  • 176161-24-3
FDA_UNII_Code
  • PTB4X93HE1
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance that blocks the ability of viruses to make new viruses and infect cells. It is being studied in the prevention of cytomegalovirus infection in cancer patients who have had a donor stem cell transplant. It is a type of antiviral agent.NCI-GLOSS
Chemical_Formula
  • C15H19Cl2N3O4
Legacy_Concept_Name
  • Maribavir
FULL_SYN
  • NTBCABNCI
  • MARIBAVIRPTFDAPTB4X93HE1
  • Benzimidazol-2-amineSNNCI
  • MaribavirPTNCI
  • BW 1263W94CNNCI
  • maribavirPTNCI-GLOSSCDR0000537249
DEFINITION
  • An orally available benzimidazole riboside compound with activity against cytomegalovirus (CMV). Maribavir is a selective ATP competitor of viral UL97 kinase, which is involved in viral nuclear maturation events, such as viral DNA assembly and movement of viral capsids from the nucleus of infected cells. Maribavir has activity against strains of CMV that are resistant to standard anti-CMV agents.NCI
code
  • C82254
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