About: Gadofosveset Trisodium Anhydrous     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Gadofosveset Trisodium Anhydrous
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Indicator, Reagent, or Diagnostic Aid
Preferred_Name
  • Gadofosveset Trisodium Anhydrous
UMLS_CUI
  • C2825433
CAS_Registry
  • 193901-90-5
FDA_UNII_Code
  • 9430ZR8ZAN
Contributing_Source
  • FDA
Chemical_Formula
  • C33H38N3O14P.Gd.3Na
Legacy_Concept_Name
  • Gadofosveset_Trisodium_Anhydrous
FULL_SYN
  • Gadofosveset Trisodium AnhydrousPTNCI
  • GADOFOSVESET TRISODIUM ANHYDROUSPTFDA9430ZR8ZAN
DEFINITION
  • The anhydrous form of gadofosveset, an injectable, intravascular, amphiphilic gadolinium-based contrast agent (GBCA) used with magnetic resonance angiography (MRA) imaging. Gadofosveset is a stable gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA) chelate derivative with a diphenylcyclohexylphosphate group. Upon injection, gadofosveset binds reversibly to endogenous serum albumin which increases its intravascular retention time compared to non-protein binding contrast agents. The serum albumin binding also increases T1-relaxivity of gadofosveset. This produces an increase in signal intensity of blood, thereby enhancing the visualization of blood vessels upon MRA and may aid in the diagnosis of certain blood vessels and heart disorders.NCI
code
  • C81058
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