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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Calfactant
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Substance
Preferred_Name
  • Calfactant
UMLS_CUI
  • C0763530
CAS_Registry
  • 183325-78-2
FDA_UNII_Code
  • Q4K217VGA9
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 658431
PDQ_Closed_Trial_Search_ID
  • 658431
Legacy_Concept_Name
  • Calfactant
FULL_SYN
  • Infasurf Intratracheal SuspensionSYNCI
  • CALFACTANTPTFDAQ4K217VGA9
  • InfasurfBRNCI
  • CalfactantPTNCI
DEFINITION
  • A sterile suspension composed of an extract of bovine pulmonary surfactant with surfactant activity. Calfactant contains phospholipids, neutral lipids, and hydrophobic surfactant-associated proteins B (SP-B) and C (SP-C). Upon intratracheal administration, this agent, mimicking endogenous pulmonary surfactant, lines the alveoli and smallest bronchioles, keeping alveoli open during expiration by lowering surface tension. Resulting improvements in lung compliance and respiratory gas exchange may lead to improvements in ventilation and oxygenation.NCI
code
  • C80989
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