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AttributesValues
rdf:type
rdfs:label
  • Degarelix Acetate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Degarelix Acetate
UMLS_CUI
  • C2609918
CAS_Registry
  • 934246-14-7
Accepted_Therapeutic_Use_For
  • advanced prostate cancer
FDA_UNII_Code
  • I18S89P20R
Contributing_Source
  • FDA
Chemical_Formula
  • C82H103ClN18O16.C2H4O2.H2O
Legacy_Concept_Name
  • Degarelix_Acetate
FULL_SYN
  • D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3- pyridinyl)-D-alanyl-L- seryl-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]- L-phenylalanyl-4-[(aminocarbonyl)amino]-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L- lysyl-L-prolyl, Acetate, HydrateSNNCI
  • FE200486 Acetate HydrateSYNCI
  • Degarelix AcetatePTNCI
  • DEGARELIX ACETATEPTFDAI18S89P20R
DEFINITION
  • The acetate form of a long-acting, synthetic peptide with gonadotrophin-releasing hormone (GnRH) antagonistic properties. Degarelix targets and blocks GnRH receptors located on the surfaces of gonadotroph cells in the anterior pituitary, thereby reducing secretion of luteinizing hormone (LH) by pituitary gonadotroph cells and so decreasing testosterone production by interstitial (Leydig) cells in the testes.NCI
code
  • C80443
is Has_Salt_Form of
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