About: Benethamine Penicillin     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Benethamine Penicillin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Benethamine Penicillin
UMLS_CUI
  • C0053102
CAS_Registry
  • 751-84-8
FDA_UNII_Code
  • O3S7RWT8R5
Contributing_Source
  • FDA
Chemical_Formula
  • C16H18N2O4S.C15H17N
Legacy_Concept_Name
  • Benethamine_Penicillin
CHEBI_ID
  • CHEBI:52151
FULL_SYN
  • Benethamine PenicillinPTNCI
  • Benethamine Penicillin GSYNCI
  • BENETHAMINE PENICILLINPTFDAO3S7RWT8R5
  • 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6- ((phenylacetyl)amino)- (2S-(2-alpha,5-alpha,6-beta))-, compd. with N-(phenylmethyl)benzeneethanamine (1:1)SNNCI
  • Benzylpenicillin salt of N-benzylphenethylamineSYNCI
  • benetacilBRNCI
DEFINITION
  • The benethamine salt of penicillin G, a member of the penicillin antibiotic family with broad-spectrum bactericidal activity. Penicillin G binds to and inactivates penicillin-binding proteins (PBPs), enzymes located on the inner membrane of the bacterial cell wall, resulting in the weakening of the bacterial cell wall and cell lysis. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.NCI
code
  • C78799
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