About: Gadoxetate Disodium     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Gadoxetate Disodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Indicator, Reagent, or Diagnostic Aid
Preferred_Name
  • Gadoxetate Disodium
UMLS_CUI
  • C0675788
CAS_Registry
  • 135326-22-6
FDA_UNII_Code
  • HOY74VZE0M
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 617182
PDQ_Closed_Trial_Search_ID
  • 617182
Chemical_Formula
  • C23H28N3O11.Gd.2Na
Legacy_Concept_Name
  • Gadoxetate_Disodium
FULL_SYN
  • Disodium (N-((2S)-2-(bis(carboxymethyl)amino)-3-(p-ethoxyphenyl)propyl)-N-(2-(bis(carboxymethyl)amino)ethyl)glycinato(5-))gadolinate(2-)SNNCI
  • Gd-EOB-DTPAABNCI
  • Gadoxetic Acid DisodiumSYNCI
  • Gd-(S)-EOB-DTPAABNCI
  • EovistBRNCI
  • Gadolinium EOB DTPASYNCI
  • Gadoxetate DisodiumPTNCI
  • Gadolinium Ethoxybenzyl Diethylenetriaminepentaacetic AcidSYNCI
  • ZK 139834CNNCI
  • GADOXETATE DISODIUMPTFDAHOY74VZE0M
  • PrimovistFBNCI
DEFINITION
  • A paramagnetic contrast agent consisting of the disodium salt of the gadolinium ion chelated with the lipophilic moiety ethoxybenzyl (EOB) bound to diethylenetriamine pentaacetic acid (DTPA). When placed in a magnetic field, gadolinium produces a large magnetic moment and so a large local magnetic field, which can enhance the relaxation rate of nearby protons; as a result, the signal intensity of tissue images observed with magnetic resonance imaging (MRI) may be enhanced. Because this agent is preferentially taken up by normal functioning hepatocytes, normal hepatic tissue is enhanced with MRI while tumor tissue is unenhanced. In addition, because this agent is excreted in the bile, it may be used to visualize the biliary system using MRI.NCI
code
  • C77548
is Has_Salt_Form of
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