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AttributesValues
rdf:type
rdfs:label
  • Cevipabulin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cevipabulin
UMLS_CUI
  • C2699167
CAS_Registry
  • 849550-05-6
FDA_UNII_Code
  • P14M0DWS2J
Contributing_Source
  • FDA
Chemical_Formula
  • C18H18ClF5N6O
Legacy_Concept_Name
  • Cevipabulin
FULL_SYN
  • CevipabulinPTNCI
  • CevipabulinumSYNCI
  • CEVIPABULINPTFDAP14M0DWS2J
DEFINITION
  • A synthetic, water soluble tubulin-binding agent with potential antineoplastic activity. Cevipabulin appears to bind at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. The disruption in microtubule dynamics may eventually inhibit cell division and reduce cellular growth.NCI
code
  • C77064
is Has_Free_Acid_Or_Base_Form of
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