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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Prednisone
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Steroid
Preferred_Name
  • Prednisone
NSC_Code
  • 10023
UMLS_CUI
  • C0032952
CAS_Registry
  • 53-03-2
Accepted_Therapeutic_Use_For
  • Inflammatory conditions; Allergic conditions; Hematologic conditions; Neoplastic conditions; Autoimmune conditions; Replacement therapy in adrenal insufficiency
In_Clinical_Trial_For
  • Graft Versus Host disease; Lymphoma(s); Leukemia(s); Multiple myeloma; Myocarditis; Neuroblastoma; Post-transplant lymphoproliferative disorder; Premature Ovarian Failure; Prostate cancer
FDA_UNII_Code
  • VB0R961HZT
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to lessen inflammation and lower the body's immune response. It is used with other drugs to treat leukemia and lymphoma and other types of cancer. It is also used alone or with other drugs to prevent or treat many other conditions. These include conditions related to cancer, such as anemia (a low level of red blood cells), allergic reactions, and loss of appetite. Prednisone is a type of therapeutic glucocorticoid.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42487
PDQ_Closed_Trial_Search_ID
  • 42487
Chemical_Formula
  • C21H26O5
Legacy_Concept_Name
  • Prednisone
CHEBI_ID
  • CHEBI:8382
FULL_SYN
  • PrednilongaSYDTPNSC0010023
  • Delta-DomeAQSNCI
  • Meprosona-FFBNCI
  • PrednilongaFBNCI
  • MeticortenAQSNCI
  • PredicortenFBNCI
  • PrednisonumSYNCI
  • prednisonePTNCI-GLOSSCDR0000045492
  • Liquid PredAQSNCI
  • Prednicen-MAQSNCI
  • DeltacorteneFBNCI
  • PrednisonePTDCP00934
  • SK-PrednisoneSYDTPNSC0010023
  • 17,21-Dihydroxypregna-1,4-diene-3,11,20-trioneSNNCI
  • 1, 2-DehydrocortisoneSYDTPNSC0010023
  • DeltraSYDTPNSC0010023
  • Sk-PrednisoneAQSNCI
  • DeltacortisoneSYNCI
  • DeltacortisoneSYDTPNSC0010023
  • PREDABNCI
  • OrasoneSYDTPNSC0010023
  • MetacortandracinSYNCI
  • Delta 1-CortisoneSYNCI
  • DacortinSYDTPNSC0010023
  • ParacortSYDTPNSC0010023
  • DecortonSYDTPNSC0009567
  • LisacortSYDTPNSC0010023
  • DeltisonSYDTPNSC0010023
  • DeltraFBNCI
  • MetacortandracinSYDTPNSC0010023
  • AdasoneFBNCI
  • DeltasoneSYDTPNSC0010023
  • ServisoneSYDTPNSC0010023
  • PREDNISONEPTFDAVB0R961HZT
  • DeCortinFBNCI
  • DacortinFBNCI
  • OrasoneAQSNCI
  • PredicorFBNCI
  • ParacortFBNCI
  • DecortonFBNCI
  • PromifenFBNCI
  • DeltisonFBNCI
  • Delta-DomeSYDTPNSC0010023
  • 1,2-DehydrocortisoneSNNCI
  • MeticortenSYDTPNSC0010023
  • DecortisylSYDTPNSC0010023
  • Panasol-SFBNCI
  • .delta.1-CortisoneSYDTPNSC0010023
  • PrednidibFBNCI
  • PanafcortFBNCI
  • LisacortAQSNCI
  • EconosoneFBNCI
  • OfisolonaFBNCI
  • CortancylFBNCI
  • ServisoneFBNCI
  • Prednicen-MSYDTPNSC0010023
  • PredeltinAQSNCI
  • SterapredAQSNCI
  • PrednimentFBNCI
  • PrednitoneFBNCI
  • PrednicortFBNCI
  • PrednisonePTNCI
  • DecortisylFBNCI
  • DeltadehydrocortisoneSYNCI
DEFINITION
  • A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations.NCI
code
  • C770
is someValuesFrom of
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