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AttributesValues
rdf:type
rdfs:label
  • Prazosin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Prazosin
UMLS_CUI
  • C0032912
CAS_Registry
  • 19216-56-9
FDA_UNII_Code
  • XM03YJ541D
Contributing_Source
  • FDA
ALT_DEFINITION
  • A selective adrenergic alpha-1 antagonist used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention.MSH2002_06_01
Chemical_Formula
  • C19H21N5O4
Legacy_Concept_Name
  • Prazosin
CHEBI_ID
  • CHEBI:8364
FULL_SYN
  • 2-[4-(2-furoyl)piperazin-1-yl]-4-amino-6,7-dimethoxyquinazolineSNNCI
  • 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazineSNNCI
  • PRAZOSINPTFDAXM03YJ541D
  • PrazosinPTNCI
  • FurazosinSYNCI
DEFINITION
  • A synthetic piperazine derivative and an alpha-1 adrenergic receptor inhibitor used primarily as an anti-hypertensive. Prazosin's effects are most pronounced in the large resistance vessels (i.e. arterioles) and result in a decrease in total systemic vascular resistance (SVR) without a rebound or reflex tachycardia. To a lesser extent, this agent also decreases the tone of the bladder sphincter, thereby allowing the opening of the bladder into the urethra and thus relieving the urinary conditions associated with benign prostatic hypertrophy.NCI
code
  • C767
is Has_Free_Acid_Or_Base_Form of
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