About: Pirbenicillin Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Pirbenicillin Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Pirbenicillin Sodium
UMLS_CUI
  • C2698821
CAS_Registry
  • 55162-26-0
FDA_UNII_Code
  • 638D8M316Y
Contributing_Source
  • FDA
Chemical_Formula
  • C24H25N6O5S.Na
Legacy_Concept_Name
  • Pirbenicillin_Sodium
FULL_SYN
  • PIRBENICILLIN SODIUMPTFDA638D8M316Y
  • Pirbenicillin SodiumPTNCI
DEFINITION
  • The sodium salt form of pirbenicillin, a broad-spectrum semisynthetic penicillin with antibacterial activity. Pirbenicillin binds to and inactivates the penicillin binding proteins (PBPs) located inside the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.NCI
code
  • C76226
is Has_Salt_Form of
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