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AttributesValues
rdf:type
rdfs:label
  • Carbenicillin Indanyl
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Carbenicillin Indanyl
UMLS_CUI
  • C0054667
CAS_Registry
  • 35531-88-5
FDA_UNII_Code
  • 5V278481KE
Contributing_Source
  • FDA
Chemical_Formula
  • C26H26N2O6S
Legacy_Concept_Name
  • Carbenicillin_Indanyl
CHEBI_ID
  • CHEBI:52015
FULL_SYN
  • CARBENICILLIN INDANYLPTFDA5V278481KE
  • Carbenicillin IndanylPTNCI
DEFINITION
  • The indanyl ester of carbenicillin, a broad-spectrum, semisynthetic penicillin derivative with antibacterial activity. Following absorption, carbenicillin indanyl is rapidly hydrolyzed to the active carbenicillin, which binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to a weakening of the bacterial cell wall, eventually causing bacterial cell lysis.NCI
code
  • C76219
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