About: Amdinocillin Pivoxil     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Amdinocillin Pivoxil
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Amdinocillin Pivoxil
UMLS_CUI
  • C0002436
CAS_Registry
  • 32886-97-8
FDA_UNII_Code
  • 1WAM1OQ30B
Contributing_Source
  • FDA
Chemical_Formula
  • C21H33N3O5S
Legacy_Concept_Name
  • Amdinocillin_Pivoxil
CHEBI_ID
  • CHEBI:51210
FULL_SYN
  • AMDINOCILLIN PIVOXILPTFDA1WAM1OQ30B
  • Amdinocillin PivoxilPTNCI
DEFINITION
  • The pivoxil ester form of a semisynthetic, broad spectrum beta-lactam penicillin with antibacterial activity. Amdinocillin specifically binds to and inactivates penicillin-binding protein 2 (PBP 2) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.NCI
code
  • C76216
is Has_Salt_Form of
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