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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cefozopran
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cefozopran
UMLS_CUI
  • C0246584
CAS_Registry
  • 113359-04-9
FDA_UNII_Code
  • 1LG87K28LW
Contributing_Source
  • FDA
Chemical_Formula
  • C19H17N9O5S2
Legacy_Concept_Name
  • Cefozopran
FULL_SYN
  • CEFOZOPRANPTFDA1LG87K28LW
  • CefozopranPTNCI
DEFINITION
  • A semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefozopran binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C76172
is Has_Free_Acid_Or_Base_Form of
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