About: Cefminox

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Cefminox
rdfs:subClassOf	Cephalosporin Antibacterial
Has_Salt_Form	Cefminox Sodium
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Cefminox
UMLS_CUI	C0055006
CAS_Registry	75481-73-1
FDA_UNII_Code	PW08Y13465
Contributing_Source	FDA
Chemical_Formula	C16H21N7O7S3
Legacy_Concept_Name	Cefminox
FULL_SYN	(6R,7S)-7-(2-(((S)-2-Amino-2-carboxyethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic AcidSNNCI CEFMINOXPTFDAPW08Y13465 CefminoxPTNCI CefminoxumSYNCI
DEFINITION	A semisynthetic, second-generation, beta-lactamase-stable cephalosporin with antibacterial activity. Cefminox binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code	C76169
is Has_Free_Acid_Or_Base_Form of	Cefminox Sodium

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