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AttributesValues
rdf:type
rdfs:label
  • Cefcapene
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cefcapene
UMLS_CUI
  • C2699134
CAS_Registry
  • 135889-00-8
FDA_UNII_Code
  • 4D5D3422MW
Contributing_Source
  • FDA
Chemical_Formula
  • C17H19N5O6S2
Legacy_Concept_Name
  • Cefcapene
FULL_SYN
  • CEFCAPENEPTFDA4D5D3422MW
  • CefcapenePTNCI
DEFINITION
  • A semisynthetic third-generation cephalosporin with antibacterial activity. Cefcapene binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C76160
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