About: Ciluprevir     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Ciluprevir
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ciluprevir
UMLS_CUI
  • C1313841
CAS_Registry
  • 300832-84-2
Accepted_Therapeutic_Use_For
  • Hepatitis C Infection
FDA_UNII_Code
  • 75C8DU40T0
Contributing_Source
  • FDA
Chemical_Formula
  • C40H50N6O8S
Legacy_Concept_Name
  • Ciluprevir
FULL_SYN
  • BILN 2061 ZWCNNCI
  • (2R,6S,12Z,13aS,14aR,16aS)-6-(((Cyclopentyloxy)carbonyl)amino)-2-((7-methoxy-2-(2-((1-methylethyl)amino)thiazol-4-yl)quinolin-4-yl)oxy)-5,16-dioxo-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa(e)pyrrolo(1,2-a)(1,4)diazacyclopentadecine-14a(5H)-carboxylic acidSNNCI
  • CILUPREVIRPTFDA75C8DU40T0
  • BILN 2061CNNCI
  • CiluprevirPTNCI
DEFINITION
  • An orally bioavailable, peptidomimetic, macrocyclic compound with activity against hepatitis C virus (HCV). Ciluprevir binds non-covalently to the active center of the HCV NS3-4A serine protease and prevents processing of viral proteins required for replication.NCI
code
  • C76016
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