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AttributesValues
rdf:type
rdfs:label
  • Phosphatidylinositol
rdfs:subClassOf
Semantic_Type
  • Lipid
Preferred_Name
  • Phosphatidylinositol
UMLS_CUI
  • C0031621
Legacy_Concept_Name
  • Phosphatidylinositol
CHEBI_ID
  • CHEBI:28874
FULL_SYN
  • PIABNCI
  • PhosphatidylinositolPTNCI
DEFINITION
  • A phosphatidic acid combined with inositol found in biomembranes and a precursor to certain cellular signals. Sometimes referred to as inositide. It is a very important minor phospholipid in eukaryotes, involved in signal transduction processes. Contains myo inositol linked through the 1 hydroxyl group to phosphatidic acid. The 4 phosphate (PIP) and 4, 5 bisphosphate derivatives PIP2) are formed and broken down in membranes by the action of specific kinases and phosphatases (futile cycles). Signal sensitive phospholipase C enzymes remove the inositol moiety, in particular from 1,4,5 trisphosphate (PIP2) as inositol 1,4,5 triphosphate (Ins P3: IP3). Both the diacyl glycerol and products act as second messengers.NCIOn-line Medical Dictionary
code
  • C743
is rdfs:subClassOf of
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