About: Phenothiazine

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Attributes	Values
rdf:type	Class
rdfs:label	Phenothiazine
rdfs:subClassOf	ANTIEMETICS
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Phenothiazine
UMLS_CUI	C0031436
CAS_Registry	92-84-2
FDA_UNII_Code	GS9EX7QNU6
Contributing_Source	FDA
ALT_DEFINITION	A type of drug that is used to treat severe mental and emotional disorders, severe nausea and vomiting, and certain other conditions. It belongs to the families of drugs called antipsychotics and antiemetics.NCI-GLOSS
Chemical_Formula	C12H9NS
Legacy_Concept_Name	Phenothiazine
CHEBI_ID	CHEBI:37931 CHEBI:38093
FULL_SYN	PHENOTHIAZINEPTFDAGS9EX7QNU6 PhenothiazinePTNCI phenothiazinePTNCI-GLOSSCDR0000467858 PhenothiazinePTDCP04869
DEFINITION	A class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain, potentially preventing chemotherapy-induced emesis. In addition, these agents have peripherally or centrally antagonistic activity against alpha adrenergic, serotonergic, histaminic, and muscarinic receptors. (NCI)NCI
code	C740
is rdfs:subClassOf of	PROMAZINE HYDROCHLORIDE PROCHLORPERAZINE EDISYLATE PROMAZINE TRIFLUOPERAZINE Levomepromazine Maleate Metofenazate THIETHYLPERAZINE MALEATE TRIFLUPROMAZINE TRIFLUPROMAZINE HYDROCHLORIDE PROCHLORPERAZINE MALEATE Levomepromazine Hydrochloride Chlorpromazine Promethazine Hydrochloride CHLORPROMAZINE HYDROCHLORIDE ACETOPHENAZINE MALEATE Carphenazine Maleate Duoperone Furomazine Imiclopazine METHOTRIMEPRAZINE Oxyridazine PIPERACETAZINE Promethazine Teoclate PROCHLORPERAZINE PROMETHAZINE TRIFLUOPERAZINE HYDROCHLORIDE PROMETHAZINE HYDROBROMIDE

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