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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Buciclovir
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Buciclovir
UMLS_CUI
  • C0050178
CAS_Registry
  • 86304-28-1
FDA_UNII_Code
  • 4G4Z4676IS
Contributing_Source
  • FDA
Chemical_Formula
  • C9H13N5O3
Legacy_Concept_Name
  • Buciclovir
FULL_SYN
  • (R)-9-(3,4-Dihydroxybutyl)guanineSNNCI
  • BCVABNCI
  • BUCICLOVIRPTFDA4G4Z4676IS
  • 2-Amino-9-((R)-3,4-dihydroxybutyl-9H-purin-6(1H)-onSNNCI
  • BuciclovirPTNCI
DEFINITION
  • An acyclic guanosine analog with activity against herpes simplex virus (HSV). Buciclovir is phosphorylated to its triphosphate form by HSV thymidine kinase in infected cells and acts as a specific inhibitor of the viral DNA polymerase. It is incorporated into both RNA and DNA but only inhibits DNA synthesis.NCI
code
  • C73198
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