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AttributesValues
rdf:type
rdfs:label
  • Colistimethate
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Colistimethate
UMLS_CUI
  • C0009315
FDA_UNII_Code
  • DL2R53P963
Contributing_Source
  • FDA
Legacy_Concept_Name
  • Colistimethate
CHEBI_ID
  • CHEBI:59662
FULL_SYN
  • COLISTIMETHATEPTFDADL2R53P963
  • ColistimethatePTNCI
DEFINITION
  • A broad-spectrum polymyxin antibiotic against most aerobic Gram-negative bacteria except Proteus bacteria. Colistimethate is a mixture of methanesulfonate derivatives of cyclic polypeptides colistin A and B from Bacillus colistinus or B. polymyxa. Colistin functions as a surfactant which penetrates into and disrupts the bacterial cell membrane, thereby resulting in bactericidal effect.NCI
code
  • C72729
is Has_Free_Acid_Or_Base_Form of
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