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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cefditoren
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cefditoren
UMLS_CUI
  • C0287573
CAS_Registry
  • 104145-95-1
FDA_UNII_Code
  • 81QS09V3YW
Contributing_Source
  • FDA
Chemical_Formula
  • C19H18N6O5S3
Legacy_Concept_Name
  • Cefditoren
CHEBI_ID
  • CHEBI:59343
FULL_SYN
  • CEFDITORENPTFDA81QS09V3YW
  • CefditorenPTNCI
DEFINITION
  • A semisynthetic, broad-spectrum, beta-lactamase-resistant, third-generation cephalosporin with antibacterial activity. Cefditoren binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C72625
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